I guess the short anser is no. I have followed these links and many others an so far it's a big no. The 3.3v slot is not likely to work for sound either. Older PCI sound cards that emulated the ISA Sound Blaster are 5v. Some motherboards had a setting in the bios to emulate Sound Blaster sound for the AC97. At this point I am living without sound. It's a shame, because the FreeDOS support is why I bought the ALIX so I could setup a nice DOS machines. But no DOS games, ouch!